Wolfsburg reached the last 16 of the German Cup with a skeleton squad after a 4-0 win over second-tier Sandhausen, after the coronavirus and injuries ruled out 11 of the Bundesliga side's players.
Four Wolfsburg players missed out after positive coronavirus tests.
Three more were in isolation because of close contact with their infected teammates.
Coach Oliver Glasner named three reserve goalkeepers among his seven substitutes, with two of the keepers dressed as outfield players.
Those emergency replacements weren't needed as Wolfsburg cruised to a straightforward win with two goals from Wout Weghorst.
Stuttgart beat Freiburg 1-0 in the only all top-division game of the day after holding on to the lead after Sasa Kalajdzic's 15th-minute goal for the hosts.
Mainz are battling against relegation from the Bundesliga and got no respite in a 3-0 loss on penalties against second-tier Bochum after extra time ended 2-2.
United States striker Josh Sargent scored as Werder Bremen breezed through with a 3-0 win over Hannover.
Fourth-tier Rot-Weiss Essen won 3-2 in an upset against Fortuna Dusseldorf, who play two divisions higher.
Jahn Regensburg came through a penalty shootout 4-2 after a goalless draw with Wehen Wiesbaden.
It was the last day of games in Germany before a shortened winter break. The Bundesliga returns on Junuary 2.