Jordan Thompson's preparations for the French Open have suffered a setback with a straight-sets loss to Miomir Kecmanovic in the second round of the ATP Tour's Generali Open.
Thompson was completely outplayed by Serbian world No.47 Kecmanovic who needed just over an hour to complete a 6-2 6-2 win at the clay-court event in Kitzbuehel, Austria.
World No.63 Thompson had his serve broken twice in each set and failed to convert on his only break-point opportunity.
Kecmanovic will face Federico Delbonis in the quarter-finals after the Argentine accounted for fourth-seeded Nikoloz Basilashvili 7-5 6-3.
The upsets continued on Thursday with the biggest casualty being top-seeded Fabio Fognini.
The Italian world No.12 was sensationally dispatched by 303rd-ranked Marc-Andrea Huesler 6-1 6-2.
Fognini, who had a bye in the opening round, was playing his first match since undergoing arthroscopic surgery on both ankles in May.
He double-faulted four times and won just eight points on serve before dropping the opening set against the Swiss qualifier in 22 minutes.
Huesler saved three break points early in the second set and held serve throughout before wrapping up the victory with a forehand winner in just 56 minutes.
It was only the third career win on the ATP tour for Huesler, who will meet Feliciano Lopez in the last eight after the veteran Spaniard took almost three hours to eliminate seventh-seeded Guido Pella 7-5 6-7 (4-7) 7-6 (7-3).
Argentine Diego Schwartzman is the only seeded player left in the tournament after his hard-fought 6-2 2-6 7-5 victory over local wildcard Sebastian Ofner.
Schwartzman, the world No.13, survived a day in which four of the tournaments eight seeds bowed out.
Third-seeded Dusan Lajovic and Polish fifth seed also exited at the clay-court tournament being played against a backdrop of the Austrian Alps ii the first ATP event in Europe since February.