Blake Schoupp re-injured his shoulder in the ACT Brumbies' final-round Super Rugby win over the Western Force, with fellow prop James Slipper also in doubt.
The Hurricanes and Blues have won their final regular-season games to finish one-two on the Super Rugby Pacific table.
After a tough week, Melbourne have fallen victim to the Fijian Drua, who ran away in the second half to secure a Super Rugby finals berth with a 40-19 win.