The Reds have made mass changes for a crucial trip to Fiji, while the Waratahs will bring Argentinian Enrique Pieretto straight in to aid their injury crisis.
The ACT Brumbies are wary of the lowly Crusaders ahead of their Heritage Round showdown with the 11-times Super Rugby champions in Canberra.
Melbourne winger Lachie Anderson says uncertainty around the club's Super Rugby future is the elephant in the room as they prepare for their final home game.