Six-time MotoGP champion Marc Marquez will miss the season-opening Qatar Grand Prix as he continues to recover from a broken arm sustained last season.
Marquez fractured his humerus in the 2020 season-opening Spanish Grand Prix in Jerez last July and did not race again all year.
The 28-year-old Spaniard has since undergone three surgeries for the injury, with Honda saying doctors advised against rushing his return to the track.
Marquez will get another medical check on April 12.
"After the last review with the medical team, the doctors have advised me that the most prudent thing was not to take part in the Qatar Grand Prix and to continue with the recovery plan that we have followed in recent weeks," Marquez said.
"I would have loved to be able to participate in the opening race of the world championship, but we will have to continue working to be able to recover the optimal conditions that allow us to return to competition."
The opening race in Qatar takes place on Sunday with the second round, the Grand Prix of Doha, also at the same circuit on April 4.