Mitchell Pearce is set to provide some welcome relief for injury-depleted Newcastle after Kalyn Ponga and Slade Griffin went down in Saturday's NRL loss to Canterbury.
After losing both fullback Ponga (hamstring) and hooker Griffin (knee) in the first half, the Knights couldn't hold out the Dogs who ran out 36-16 winners at McDonald Jones Stadium.
It's unclear whether Ponga will be fit for State of Origin II after being awkwardly twisted in a Lachlan Lewis tackle and limping from the field in the 14th minute.
While Griffin was taken to hospital in severe pain and it was feared he had suffered the fourth torn ACL of his luckless career.
Knights coach Nathan Brown said it was possible that Griffin had torn several different ligaments but it was too early to provide a diagnosis.
"Kalyn's got a hamstring injury. He'll have a scan tomorrow. To what extent it is - I don't know whether it's a short one or a long one," Brown said.
"Slade is at hospital, he's in a lot of pain. Whether he's got one ligament or multiple ligament damage, we won't know until tomorrow. He's certainly not in a good way."
The Knights hope to welcome back skipper Pearce against Parramatta at home after the bye.
Pearce has been on the sidelines since injuring his pec in round seven and is closing in on a return along with Daniel Saifiti (foot) and Nathan Ross (groin).
"We've had Pearcey out for a while. We've had a lot of pressure on Cogs (Jack Cogger) to do things which is a little unfair on him at this stage of his career," Brown said.
"Fortunately I think we'll get Pearcey back for the next game, which will help take a lot of pressure off Cogs and Connor (Watson) and them blokes and they'll be allowed a little bit more what suits them."
Another serious knee injury could spell the end of Griffin's career - just a week after he made his international debut for New Zealand.
The 27-year-old has endured a horror run of luck and at one point went three years between NRL appearances because of injury.
"I just know that it's probably not great. Where it's at, they're not 100 per cent sure," Brown said.
"It's not good. We've just crossed our fingers, take our club out of the equation, Slade's had a tough time throughout his career with his ACL, I just hope it's a good result."