Marcus Rashford has fired Manchester United to victory at Real Betis with a rocket of a strike as Erik ten Hag's side cruised through to the Europa League quarter-finals.

The Red Devils headed to Spain all-but assured of progress from this last-16 tie having won the first leg 4-1 in freezing conditions at Old Trafford last Thursday.

Betis made United sweat during the opening stages in the return fixture, but Rashford's outstanding strike silenced the bouncing Estadio Benito Villamarin and secured a 1-0 win on the night.

The impressive 5-1 aggregate triumph puts them through to the quarter-finals, with Friday's draw to outline their potential path to the Europa League final in Budapest.

The second leg in Seville had started in unconvincing fashion against Manuel Pellegrini's Verdiblancos, with Juanmi wasting a glorious chance before Joaquin struck the post from distance.

Facundo Pellistri, making his first United start, hit the post at the end of a poor first half that was followed by a much-improved second-period performance by Ten Hag's team.

Rashford looked sharp and followed an inexplicable miss moments earlier by unleashing a stunning 25-metre strike that ensured United's first away trip since their Anfield annihilation ended in a win.

Ten Hag was content with the way his side closed out the tie.

"I'm happy, but we like challenges. We knew before that Betis was a really good team, we have seen that against Real Madrid and Barcelona, but we've beaten them twice so we've performed well," he told BT Sport.

"The second half we were much better on the ball, more calm. We kept the ball in the opposition half, let them run, and then you create chances."

Arsenal, however, were knocked out after losing to Sporting Lisbon on penalties following a 1-1 draw in the second leg at the Emirates Stadium. The tie finished 3-3 on aggregate.

Jerry St Juste was first up for the visitors in the shootout and smashed his spot-kick past Ramsdale, who guessed the right way.

Odegaard then stepped up for Arsenal and calmly slotted home before Ricardo Esgaio re-established the lead.

Saka was the next Arsenal man to tuck away from 12 yards and while Ramsdale got a hand to Goncalo Inacio's effort he couldn't keep it out as Trossard continued the scoring run to make it 3-3.

Arthur Gomes' penalty then sneaked in as Ramsdale again came close to saving, but Gabriel Martinelli saw his effort saved by Adan to put Sporting on the cusp.

Santos made no mistake as he smashed home to send the visitors through 5-3 on penalties, to leave Arsenal still without a home knockout win in Europe since May 2019.

In other ties, Juventus cantered into the quarters with a 2-0 win at Germany's Freiburg, giving them a 3-0 victory on aggregate.

Dusan Vlahovic netted a penalty just before the break after Manuel Gulde was sent off following a handball, with substitute Federico Chiesa then wrapping up the win in stoppage time.

Jose Mourinho's Roma drew 0-0 with Real Sociedad to advance 2-0 on aggregate while Leverkusen beat Ferencvaros 2-0 for a 4-0 win in the tie.

Union Saint-Gilloise defeated Union Berlin 3-0 to advance 6-3.

In the Netherlands, Feyenoord thrashed Ukraine's Shakhtar Donetsk 7-1 to progress 8-2 on aggregate as captain Orkun Kokcu and forward Oussama Idrissi each scored twice.

In Turkey, record six-times Europa League winners Sevilla had to dig deep against Fenerbahce, who won the second leg 1-0 thanks to Enner Valencia's penalty but the Spanish side made the last eight 2-1 on aggregate.