Flyhalf Matthieu Jalibert will miss France's Six Nations decider against Scotland after hurting his jaw in the epic 32-30 win against Wales.
He will be replaced in the squad by Louis Carbonel, the French Rugby Federation said on Sunday.
Jalibert's starting spot against Scotland is expected to go to Romain Ntamack, who did well when he replaced Jalibert against Wales on Saturday, with Carbonel on the bench as backup at Stade de France on Friday.
France still have a chance to pip Wales to the title after denying the visitors a record-equaling 13th grand slam in a pulsating game, which France won with an injury-time try from fullback Brice Dulin.
To win a first Six Nations title in 11 years, France need another bonus-point win and have to hope they score enough to beat Wales on points difference.
The 22-year-old Carbonel, who has three Test caps, is no stranger to high-pressure games as the latest player to come through from France's under-20 world champion teams.
Carbonel kicked the winning penalty with 15 minutes remaining to give France a 24-23 win over Australia in the 2019 world under-20 final, a year after starring on home soil by kicking 23 points in the 2018 final against England.