Premier League side Leeds United have suffered the biggest upset of the FA Cup third round in losing 3-0 at fourth-tier Crawley Town but their was no such drama for competition heavyweights Tottenham Hotspur, Manchester City and Chelsea.
Spurs enjoyed a 5-0 win at minnows Marine AFC, City strolled past Championship side Birmingham City 3-0 and the Blues defeated League Two side Morecambe 4-0.
Premier League strugglers Brighton & Hove Albion narrowly avoided a huge upset as they accounted for fourth-tier Newport County 4-3 on penalties in South Wales.
At Broadfield Stadium, a brilliant solo strike from Nick Tsaroulla in the 50th minute put Crawley in front, after a first half in which Leeds dominated possession but caused them few problems.
The lead was doubled three minutes later as Leeds keeper Kiko Casilla let an Ashley Nadesan shot squeeze in at the near post.
The impressive Nadesan had a hand in Crawley's third when his low shot was parried out by Casilla, only for Jordan Tunnicliffe to pounce and drill the ball home.
Summing up the 'magic of the FA Cup' was the sight of Mark Wright coming on for Crawley as a late substitute.
The 33-year-old Wright has taken part in reality TV shows "The Only Way Is Essex," "I'm A Celebrity, Get Me Out Of Here!" and "Strictly Come Dancing".
He has continued to pursue his dream of becoming a professional soccer player, and joined Crawley last month on a non-contract basis.
Crawley boss John Yems said the magnitude of the win over Marcelo Bielsa's side would take some time to comprehend.
"It won't sink in until possibly when you're lying on a beach in the summer and there's people talking about it and you see the re-runs of what the club has done and who you beat," he said.
Jose Mourinho's Tottenham travelled to Merseyside to face eighth-tier Marine - a team of part-timers that play in the Northern Premier League, Division One North West and sit 161 places below Spurs in the English football pyramid.
The non-leaguers went close to opening the scoring on 20 minutes when Neil Kengni struck the bar with a long-range effort before Tottenham took control.
A Carlos Vinicius hat-trick and further goals from Lucas Moura and Alfie Devine - who came on as a substitute at the break to become Spurs' youngest player at 16 years and 163 days old - ensured no fairytale win for the hosts.
Bernardo Silva scored two goals and Phil Foden the other as Man City eased past Birmingham while Frank Lampard's Chelsea accounted for Morecambe with goals from Mason Mount, Timo Werner, Callum Hudson-Odoi and Kai Havertz.
Championship clubs Barnsley and Bristol City also advanced on Sunday.