Injured Brad Smith could be sidelined indefinitely, the manager of the Socceroo's EPL club says.
Bournemouth boss Eddie Howe is resigned to losing Smith for an extended period after the defender suffered a hip muscle problem on international duty with Australia.
Smith will be missing from Bournemouth's side to play Tottenham at Wembley and Howe fears the injury could be long term.
"Brad is the major worry," Howe told the Bournemouth Daily Echo.
"He looks like he has got a nasty injury but we don't know the full extent. He has had one scan but we want to get it confirmed.
"It looks like he could be out for a period of time.
"I don't have an exact time for you but he seems to have a hip problem related to his quad muscle."
Smith was a controversial inclusion in under-fire national coach Ange Postecoglou's 23-man World Cup qualifying squad to take on Syria after a mediocre performance in Australia's 2-0 loss to Japan.
But he lasted just 11 minutes in a dramatic return-leg tie, won 2-1 by the Socceroos in Sydney, leaving the field with a hip flexor injury and being replaced by Huddersfield's Aaron Mooy.
Adding to Bournemouth's woes, the Cherries will also be without Scotland midfielder Ryan Fraser who has picked up a hamstring injury.
Norway forward Josh King has a similar injury, but neither is expected to be long-term absentees.
Defender Tyrone Mings has been out with a back problem, while forward Callum Wilson continues to step up his rehabilitation after a serious knee injury.
Provisional Bournemouth squad: Begovic, Ake, Francis, A Smith, Daniels, L Cook, Stanislas, Pugh, Surman, Afobe, Defoe, Boruc, S Cook, Boruc, Gosling, Mousset, Arter, Ibe.