London, a first-round pick in 2022, was held out of practice all week before the Falcons (4-4) officially ruled him out Friday. He tops the team with 37 receptions for 438 yards and two touchdowns.
While London's injury wasn't as serious an initially feared, it will keep him out of a game for the first time in his young pro career.
London's absence will make things tougher on Taylor Heinicke, who gets his first start for Atlanta at quarterback in place of Desmond Ridder. Mack Hollins (14 catches) is the other wideout with double-figure receptions this season.
The Falcons also will be without fullback Keith Smith (concussion) and safety DeMarcco Hellams (hamstring). Earlier in the week, Atlanta placed defensive tackle Grady Jarrett on injured reserve with a season-ending knee injury.
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