Dak Prescott has thrown for 276 yards and two touchdowns as five-time Super Bowl champions Dallas scored their biggest road win in franchise history.
The Cowboys ran away from the Vikings in Minnesota, winning 40-3 on Sunday.
Prescott completed 22-of-25 passes for Dallas (7-3) and didn't suffer any sacks in a near-perfect performance. He was bolstered by a rushing attack that saw Tony Pollard and Ezekiel Elliott combine for 122 yards on the ground. Elliott had two rushing touchdowns, while Pollard hauled in six passes for 109 yards and two TDs in the air attack.
The loss for the Vikings (8-2) snapped a seven-game winning streak. Kirk Cousins was ineffective in the passing game, totalling just 105 yards through the air while completing 12-of-23 passes.
"This league has a way of humbling any football team at any point in time if you don't play good football," Vikings coach Kevin O'Connell said.
After Minnesota's field goal tied the game in the first quarter, Dallas responded with 37 straight points.
The Cowboys' win featured a 60-yard field goal from kicker Brett Maher, who made four field goals, and is now a perfect four-of-four in field goal attempts from 60 yards or longer.
The Eagles (9-1) trailed 13-3 entering the fourth quarter on Sunday before Hurts threw a touchdown pass and rushed for the go-ahead score to finish with 190 passing and 86 rushing yards.
Burrow completed 24-of-39 passes for 355 yard with three of his scoring strikes went to backup running back Samaje Perine.
In Massachusetts, Marcus Jones returned a punt 84 yards for a touchdown with five seconds remaining as the New England Patriots picked up their 14th consecutive win over the New York Jets, escaping with a 10-3 victory.
In a game that featured 17 punts, Jones provided the only touchdown to lead the Pats to their third straight win. New England's defence was suffocating, holding New York to just two yards of total offence in the second half and 103 for the entire game.
"I'm in disbelief ... It's a tough loss," Jets cornerback D.J. Reed said.
Atlanta's Younghoe Koo kicked a go-ahead 53-yard field goal late in the fourth quarter and Cordarrelle Patterson set an NFL record with his ninth career kick-off return for a touchdown to lift the Falcons to a 27-24 home win over the Chicago Bears.