Roy Hodgson’s side suffered a narrow defeat to Burnley last time out, leaving them 11th place in the table with four wins so far.
Newcastle are two points and four places worse off, and have lost back-to-back games of late against Southampton and Chelsea either side of the international break.
FOLLOW LIVE: Crystal Palace vs Newcastle updates
Neither side have any real early-season fears over being drawn into a relegation battle, but consistency is a big issue for both if they hope to push into the top half of the table.
Here’s everything you need to know ahead of the game.
We may earn commission from some of the links in this article, but we never allow this to influence our content.
When is the match?
The game kicks off at 8pm on Friday, 27 November at Selhurst Park.
Where can I watch it?
The match is being shown live on Amazon Prime Video. If you're not an Amazon Prime Video subscriber start a free 30-day trial here. The game can be watched via the website or app on a device or on a smart TV.
What is the team news?
Luka Milivojevic is suspended and Wilf Zaha is likely to again miss the game after testing positive for Covid-19. James Tomkins is a doubt, while Wayne Hennessey and Nathan Ferguson continue to be sidelined through injury.
Newcastle are without goalkeeper Martin Dubravka, winger Ryan Fraser, defender Paul Dummett and striker Dwight Gayle. Callum Wilson and Jamaal Lascelles are doubts. Newcastle also have a couple of players self-isolating after Covid-19 tests, but they have not disclosed who.
Palace XI: Guaita, Clyne, Dann, Cahill, Van Aanholt, Townsend, Kouyate, McArthur, Eze, Ayew, Schlupp
Newcastle XI: Darlow, Manquillo, Fernandez, Clark, Lewis, Shelvey, Hendrick, S. Longstaff, Almiron, Joelinton, Wilson
Palace - 7/5
Draw - 23/10
Newcastle - 5/2
It’s unlikely either side will go all-out for the win and it will likely be a tight, undramatic affair for most of the match. Don’t be surprised if the points are won late on. Palace 1-0 Newcastle.
This weekend get a £10 free bet with Betfair, when you bet £10 on a Same Game Multi on the Premier League. Terms: Min £10 Same Game Multi bet on any EPL match this Fri - Sun. Free bet valid for 72 hours, awarded at bet settlement. Excludes cashed out bets. T&Cs apply.