Adelaide remain unsure whether injured pair Rory Laird and Tom Lynch will be available for their must-win AFL clash against Hawthorn.
The Crows are waiting to see how Laird (hand) and Lynch (side strain) train on Thursday before deciding whether to recall them for Saturday night's match at the MCG.
Adelaide's injury plague has claimed another victim, with defender Luke Brown (ankle) ruled out as they try to arrest a three-game losing streak.
By contrast, the Hawks could take an unchanged side into this weekend.
West Coast will unveil their seventh debutant of the year on Friday night when 195cm forward Jarrod Brander replaces Jack Darling (ankle).
The Eagles are also set to regain star on-baller Luke Shuey from a hamstring injury for the SCG blockbuster against Sydney, while Kieren Jack is a likely inclusion for the Swans.
Brownlow Medallist Dustin Martin is a near-certain inclusion for Richmond's massive Sunday clash against Geelong at the MCG.
Small forward Daniel Rioli continues to impress in the VFL after returning from a broken foot and he is on the verge of his first senior game this season.
Geelong have lost Aaron Black for the year with a knee reconstruction and Jackson Thurlow is likely to take his place,.
Cory Gregson's five-goal VFL haul has put him in the selection mix.
Fremantle will regain suspended captain Nat Fyfe for Saturday's away match against Carlton and ruckman Aaron Sandilands (concussion) could also return.
St Kilda's Jack Billings responded to his demotion with a 50-plus possession game in the VFL, meaning he is set for a speedy AFL return.
The Saints will regain Jake Carlisle from suspension for their must-win game against Gold Coast at Metricon Stadium on Saturday and Jarryd Lyons could be back for the Suns.