Calderon made her debut in the Japanese single-seater series last month at Motegi, and was the only one of the series' four internationally-based foreign drivers to race amid the travel restrictions imposed in the wake of the global coronavirus pandemic.
However, taking part in last weekend's Le Mans 24 Hours for the Richard Mille Racing LMP2 team has rendered Calderon ineligible to race at Okayama because she is unable to serve the mandatory two-week quarantine period.
Now Drago Corse has announced its solo entry will be driven by Honda SUPER GT driver and championship leader Koudai Tsukakoshi.
The 33-year-old is a Super Formula veteran but was left without a drive in this year's series when the Real Racing team pulled its one-car entry.
Kenta Yamashita, Kondo Racing