Hawthorn have recalled captain Luke Hodge to face Essendon on Friday night, while Bombers speedster Jason Winderlich has been named after 15 months on the sidelines.
Hodge has been selected for just his third AFL game of the season and first since Round 6 following a lengthy absence with a knee injury.
The key midfielder starred in his VFL return last weekend, racking up 24 possessions for Box Hill, and has showed no signs of discomfort throughout training this week.
Hawks defender Brent Guerra is back from suspension for the blockbuster at Etihad Stadium, with Thomas Murphy and Kyle Cheney omitted.
Winderlich, who has not played since rupturing his anterior cruciate ligament in Round 4 last season, is one of three additions for the Bombers alongside Heath Hocking and Alex Browne.
They have replaced Ricky Dyson (ankle), David Myers (achilles) and Cory Dell'Olio (omitted).
Carlton ruckman Matthew Kreuzer has been included for Saturday night's crunch game against Richmond at the MCG.
Kreuzer missed last week's gutsy win over the Western Bulldogs with a hip complaint that has troubled him since the Round 15 victory over Collingwood.
But the Blues have named the 2007 top draft pick alongside Kane Lucas, Marcus Davies and Zach Tuohy, while Paul Bower, Jordan Russell, Matthew Watson and Nick Duigan have been dropped.
The Tigers have made one change for what shapes as a potential elimination final, with experienced forward Jake King returning from a knee injury to replace Brett O'Hanlon (omitted).
The Magpies have rested star players Harry O'Brien (groin), Dale Thomas (ankle), Steele Sidebottom (quad), Darren Jolly (soreness) for Saturday's match against Greater Western Sydney at Skoda Stadium.
Martin Clarke, Cameron Wood, Ben Sinclair and Simon Buckley are in for Collingwood, while the Giants have recalled six players including Chad Cornes plus young forwards Jonathon Patton and Jeremy Cameron.
Geelong will welcome back Brownlow medallist Jimmy Bartel and Allen Christensen against Adelaide at Simonds Stadium on Saturday.
Matthew Scarlett (suspended) and Jordan Murdoch (omitted) are out for the reigning premiers, while the Crows have promoted Taylor Walker and Luke Thompson as replacements for Kurt Tippett (concussion) and Andy Otten (knee).
Sydney have made two changes for Saturday night's clash against Gold Coast at Metricon Stadium, with Trent Dennis-Lane and Luke Parker coming in for Shane Mumford (knee) and Andrejs Everitt (omitted).
The Suns will be without Michael Rischitelli (knee) for at least one week, while Sam Day (rested) and Josh Hall (omitted) have made way for Danny Stanley, Taylor Hine and Steven May.
Melbourne have called on Brent Moloney, Jordie McKenzie and James Sellar for Brad Green's 250th game against North Melbourne at Etihad Stadium on Saturday.
Ricky Petterd, Thomas Couch and James Magner have been axed for the Demons, while the Kangaroos have made no changes to the side that beat Richmond by four points last weekend.
Port Adelaide have lost Jasper Pittard (ribs) for Sunday's fixture against Fremantle at AAMI Stadium, with Jarrad Redden, Cameron Hitchcock, Ben Jacobs and Darren Pfeiffer named on an extended bench.
The Dockers have regained midfielder Nat Fyfe from a lengthy spell with a shoulder injury, while Christopher Mayne, Lachie Neale and Zac Dawson have also been selected in an extended squad.
West Coast have recalled Luke Shuey from suspension and Josh Hill from a hamstring injury in an extended squad for Sunday's meeting with Brisbane at Patersons Stadium.
The Lions have named two potential debutants in Sam Docherty and Stephen Wrigley on an extended bench, while Aaron Cornelius and Jared Polec have been dropped.
St Kilda have included Farren Ray, Tom Ledger and Beau Wilkes in a 25-man squad for Sunday's clash against the Bulldogs at Etihad Stadium.
The Dogs have already made a host of changes, with Shaun Higgins (hamstring), Mark Austin (wrist), Ayce Cordy and Nathan Djerrkura (both omitted) out of the side.